P-177: Relation of ambulatory pulse pressure with hypertensive left ventricular hypertrophy

Pulse pressure (PP) and left ventricular hypertrophy (LVH) are an independent predictor of cardiac risk in patients with essential hypertension. However, their interconnection is not examined enough. Aim of the study is assessment of relationships between ambulatory pulse pressure with clinical parameters at hypertensive patients with LVH. 73 hypertensive patients were analysed (43 male), average age 56.3 ± 8.5 with echocardiographic LVH (left ventricular mass index: 163.5 ± 31,8 g/m2). Each subject underwent two-dimensional and Doppler echocardiography, 12-lead electrocardiogram examination, exercise stress testing (Bruce - protocol), 24-hour ambulatory blood pressure monitoring, and 24-hour Holter monitoring (analysis of ventricular arrhythmias and heart rate variability). Patients were grouped as follows: PP 59 mm Hg (Gr. 4, n=23). Strong negative relationship between ambulatory PP is recorded with heart rate variability parameters (standard deviation NN intervals - SDNN, R=-0.24, p