P-556: Ct-guided treatment of functioning SR-adenomas: a comparative study between ethanol injection and radiofrequency

We compared the results of the treatment of functioning SR adenomas using percutaneous ethanol injection (PEI) in 54 patients in the last four years and radiofrequency thermal ablation (RFTA) in 16 patients in the last one a half year. We analysed and compared clinical improvement including blood pressure (BP), lab values of plasma renin activation (PRA), plasma concentration of aldosterone (PCA), reduction of drugs intake and correlated age and time of high BP diagnosis in each one of the methods. Complications and hospital stay were also compared. Results consisted in clinical control of PRA, PCA and PCA/PRA values and BP measurements six months after the therapeutical procedures. By PEI we achieved normal BP in 33 patients (61,1%). In the remaining patients of this group, we reduced the diary intake of antihypertensive drugs in 16; in 5 patients we didn't get any results. This means that we could obtain by this method a good result in an overall of 49 of the 54 patients. In the group treated by RFTA we achieved normal BP in 11 patients (68,7 %). From the remaining 5, one is still taking three drugs, two are taking two, and one is taking one drug for the control of BP. The hospital stay was meanly 3 days for both methods. The results obtained by RFTA are comparable to those achieved by PEI (the difference is not statistically significant). Both methods have reduced costs, are easy to accomplish and less invasive than surgery; they are better accepted by the patients improving significantly their life quality. Am J Hypertens (2004) 17, 236A–236A; doi: 10.1016/j.amjhyper.2004.03.630