A Patient with Prolonged Paralysis/Commentary/Commentary
Acetylcholinesterase is distributed in the gray matter of the central nervous system, where it terminates synaptic transmission by specifically hydrolyzing the neurotransmitter acetylcholine (1, 2 ). Because succinylcholine binds to the BChE active site, its presence in plasma will produce falsely d...
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Veröffentlicht in: | Clinical chemistry (Baltimore, Md.) Md.), 2012-03, Vol.58 (3), p.496 |
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creator | Whittington, JoDell E Pham, Hoai D Procter, Melinda Grenache, David G Mao, Rong Despotis, George Goodall, Roberta |
description | Acetylcholinesterase is distributed in the gray matter of the central nervous system, where it terminates synaptic transmission by specifically hydrolyzing the neurotransmitter acetylcholine (1, 2 ). Because succinylcholine binds to the BChE active site, its presence in plasma will produce falsely decreased BChE activity and DN results. Author Contributions: All authors confirmed they have contributed to the intellectual content of this paper and have met the following 3 requirements: (a) significant contributions to the conception and design, acquisition of data, or analysis and interpretation of data; (b) drafting or revising the article for intellectual content; and (c) final approval of the published article. |
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source | Oxford Academic Journals (OUP) |
subjects | Central nervous system Drug dosages Enzymes Fluorides Genotype & phenotype Intubation Mutation |
title | A Patient with Prolonged Paralysis/Commentary/Commentary |
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