A Patient with Prolonged Paralysis/Commentary/Commentary

Acetylcholinesterase is distributed in the gray matter of the central nervous system, where it terminates synaptic transmission by specifically hydrolyzing the neurotransmitter acetylcholine (1, 2 ). Because succinylcholine binds to the BChE active site, its presence in plasma will produce falsely d...

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Veröffentlicht in:Clinical chemistry (Baltimore, Md.) Md.), 2012-03, Vol.58 (3), p.496
Hauptverfasser: Whittington, JoDell E, Pham, Hoai D, Procter, Melinda, Grenache, David G, Mao, Rong, Despotis, George, Goodall, Roberta
Format: Artikel
Sprache:eng
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Zusammenfassung:Acetylcholinesterase is distributed in the gray matter of the central nervous system, where it terminates synaptic transmission by specifically hydrolyzing the neurotransmitter acetylcholine (1, 2 ). Because succinylcholine binds to the BChE active site, its presence in plasma will produce falsely decreased BChE activity and DN results. Author Contributions: All authors confirmed they have contributed to the intellectual content of this paper and have met the following 3 requirements: (a) significant contributions to the conception and design, acquisition of data, or analysis and interpretation of data; (b) drafting or revising the article for intellectual content; and (c) final approval of the published article.
ISSN:0009-9147
1530-8561