Esterase profile of O-phosphorylated ethyltrifluorolactates in prediction of their therapeutic and toxic effects

The purpose of this study was to develop a methodology for predicting therapeutic and toxic effects of cholinesterase inhibitors by analyzing their esterase profile using homologous O phosphorylated trifluorolactates (PFLs) as an example.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Doklady. Biochemistry and biophysics 2012-04, Vol.443 (1), p.81-85
Hauptverfasser:	Rudakova, E. V., Makhaeva, G. F., Galenko, T. G., Aksinenko, A. Yu, Sokolov, V. B., Richardson, R. J., Martynov, I. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Biophysics and Molecular Biology Cholinesterase Inhibitors - adverse effects Cholinesterase Inhibitors - pharmacology Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Esterases - antagonists & inhibitors Humans Hydrophobic and Hydrophilic Interactions Inhibitor drugs Lactates - chemistry Life Sciences Organophosphorus Compounds - adverse effects Organophosphorus Compounds - chemistry Organophosphorus Compounds - pharmacology Pharmacology Phosphorylation Research methodology Structure-Activity Relationship Toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!