Infrastructures in Precision Medicine Oncology: Biobanks, Biomedical Informatics, and Big Data

At the very heart of current and future applications of precision medicine in oncology are the generation, storage, and analy sis of massive quantities of data. These large-scale data sets, the sizes of which are continuing to grow exponentially over short periods of time, include biospecimenrelated data falling under the heading of “omics”: collections of data related to the genomics, transcriptomics, proteomics (ie, large-scale analy sis of proteins), metabolomics (ie, large-scale analy sis of cellular metabolites), and other molecular characteristics of cancer. In addition, informationdense, patient-specific clinical data mined from electronic health rec ords (EHRs) from a large group of