Oxidized Phosphatidylcholines: Pattern Recognition Ligands for Multiple Pathways of the Innate Immune Response

Oxidized Phosphatidylcholines: Pattern Recognition Ligands for Multiple Pathways of the Innate Immune Response

Evolution has provided humans with various means to cope with oxidative insults and challenges. A growing body of evidence suggests that distinct host defense mechanisms have evolved to dispose of damaged molecular complexes.

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Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2002-10, Vol.99 (20), p.12515-12517
Hauptverfasser: Hazen, Stanley L., Chisolm, Guy M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
CD36 Antigens - metabolism
Cellular Senescence
Cholesterols
Commentaries
Humans
Immune system
Immune System - metabolism
Inflammation
Inflammation - metabolism
Innate immunity
Ligands
Lipids
Lipoproteins
Lipoproteins, LDL - metabolism
Mice
Models, Biological
Molecular biology
Oxidation
Oxygen - metabolism
Pattern recognition
Phosphatidylcholines
Phosphatidylcholines - metabolism
Protein Binding
Receptors
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Beschreibung
Zusammenfassung:Evolution has provided humans with various means to cope with oxidative insults and challenges. A growing body of evidence suggests that distinct host defense mechanisms have evolved to dispose of damaged molecular complexes.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.212532799