Microbial Polyketide Synthases: More and More Prolific

Microbial Polyketide Synthases: More and More Prolific

Combinatorial biosynthesis has been especially successful with bacterial polyketide synthases, enzymes that, in essence, polymerize simple fatty acids into a myriad of chemical structures called "polyketides."

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1999-03, Vol.96 (7), p.3336-3338
1. Verfasser: Hutchinson, C. Richard
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Bacteria
Bacteria - enzymology
Biosynthesis
Cloning, Molecular - methods
Commentary
Enzymes
Fatty acids
Genes
Genetic Engineering
Macrolides
Metabolites
Microbiology
Multienzyme Complexes - biosynthesis
Polyketides
Polymers
Proteins
Recombinant Proteins - biosynthesis
Saccharopolyspora - enzymology
Streptomyces - enzymology
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Beschreibung
Zusammenfassung:Combinatorial biosynthesis has been especially successful with bacterial polyketide synthases, enzymes that, in essence, polymerize simple fatty acids into a myriad of chemical structures called "polyketides."
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.96.7.3336