Fit for Life in the Immune System? Surrogate L Chain Tests H Chains That Test L Chains

Antibody molecules (Igs), built of heavy (H) and light (L) chains, are made by B-lymphocytes. L chains are composed of two muH chains of five Ig domains.

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Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1999-03, Vol.96 (6), p.2571-2573
1. Verfasser:	Melchers, Fritz
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino acids Animals B lymphocytes Commentary Gene Rearrangement, B-Lymphocyte Genes Genes, Immunoglobulin Genetic loci Humans Immune System Immunoglobulin constant regions Immunoglobulin Heavy Chains - genetics Immunoglobulin Heavy Chains - immunology Immunoglobulin Light Chains - genetics Immunoglobulin Light Chains - immunology Lead Lymphocytes Molecular chains Molecules Proteins Receptors Sequence homology
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Beschreibung
Zusammenfassung:	Antibody molecules (Igs), built of heavy (H) and light (L) chains, are made by B-lymphocytes. L chains are composed of two muH chains of five Ig domains.
ISSN:	0027-8424 1091-6490
DOI:	10.1073/pnas.96.6.2571