Immunoreactive Somatostatin is Present in Discrete Cells of the Endocrine Pancreas

A discrete population of cells of the endocrine pancreas contains immunoreactive somatostatin as shown by immunofluorescence. These cells are different from those containing glucagon or insulin. This unexpected observation may be of physiopathological significance in the regulatory mechanisms involv...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1975-04, Vol.72 (4), p.1340-1343
1. Verfasser:	Dubois, Maurice P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antiserum Cats Cellular immunity Chickens Cross Reactions Delta cells Fluorescent Antibody Technique Fluorescent antibody techniques Glucagon Humans Insulin Insulin Antibodies Islets of Langerhans Neurons Pancreas Pancreas - analysis Pancreas - immunology Pancreatic cells Rabbits - immunology Rats Secretion Sheep Somatostatin - immunology Species Specificity Swine
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Beschreibung
Zusammenfassung:	A discrete population of cells of the endocrine pancreas contains immunoreactive somatostatin as shown by immunofluorescence. These cells are different from those containing glucagon or insulin. This unexpected observation may be of physiopathological significance in the regulatory mechanisms involved in the secretion of glucagon and insulin.
ISSN:	0027-8424 1091-6490
DOI:	10.1073/pnas.72.4.1340