High-amylose wheat generated by RNA interference improves indices of large-bowel health in rats

Foods high in resistant starch have the potential to improve human health and lower the risk of serious noninfectious diseases. RNA interference was used to down-regulate the two different isoforms of starch-branching enzyme (SBE) II (SBEIIa and SBEIIb) in wheat endosperm to raise its amylose conten...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2006-03, Vol.103 (10), p.3546-3551
Hauptverfasser:	Regina, A, Bird, A, Topping, D, Bowden, S, Freeman, J, Barsby, T, Kosar-Hashemi, B, Li, Z, Rahman, S, Morell, M
Format:	Artikel
Sprache:	eng
Schlagworte:	1,4-alpha-Glucan Branching Enzyme - antagonists & inhibitors 1,4-alpha-Glucan Branching Enzyme - genetics 1,4-alpha-Glucan Branching Enzyme - metabolism amylose Amylose - metabolism Animals Biological Sciences Biology carbohydrate content Carbohydrates cecum Corn Diet Digesta digestion Endosperm Enzymes Fatty acids food intake Food, Genetically Modified gastrointesinal health gene silencing Genetic Engineering genetically modified foods Glucans - chemistry Health Health Status hexosyltransferases Humans Industrial research Intestine, Large - metabolism Isoenzymes - antagonists & inhibitors Isoenzymes - genetics Isoenzymes - metabolism large intestine Male Plants, Genetically Modified Protein isoforms Rats Rats, Sprague-Dawley Regional identity Ribonucleic acid RNA RNA Interference Rodents short chain fatty acids Small intestine Starch - chemistry Starch - metabolism starch branching enzyme Starches Transgenic plants Triticum - genetics Triticum - metabolism Triticum aestivum Wheat wheat starch
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