Network meta-analysis of the efficacy of endoscopic cardia peripheral tissue scar formation (ECSF) in the treatment of gastroesophageal reflux disease

Endoscopic antireflux therapy is widely used in clinical practice. Peroral endoscopic cardial constriction (PECC), antireflux mucosal intervention (ARMI), and radiofrequency ablation (RF) possess analogous antireflux mechanisms. This comprehensive systematic review and meta-analysis aimed to evaluat...

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Veröffentlicht in:	PloS one 2024-12, Vol.19 (12), p.e0311208
Hauptverfasser:	Shi, Chaoyi, Zhou, Shunhai, Chen, Xuanran, Shen, Diyun, Wang, Tianyue, ZhuoMa, GeSang, Feng, Mingzhi, Sun, Yan, Zhang, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Ablation (Surgery) Adverse events Cardia - pathology Cardia - surgery Care and treatment China Cicatrix - pathology Cohort analysis Diseases Dysphagia Effectiveness Endoscopy Esophagus Evidence-based medicine Gastroesophageal reflux Gastroesophageal Reflux - pathology Gastroesophageal Reflux - surgery Gastroesophageal Reflux - therapy Health services Humans Intervention Medical research Medicine and Health Sciences Medicine, Experimental Meta-analysis Network Meta-Analysis Patient satisfaction Patients People and Places Physical Sciences Proton pump inhibitors Radio frequency Research and Analysis Methods Statistical analysis Surgery Treatment Outcome
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Zusammenfassung:	Endoscopic antireflux therapy is widely used in clinical practice. Peroral endoscopic cardial constriction (PECC), antireflux mucosal intervention (ARMI), and radiofrequency ablation (RF) possess analogous antireflux mechanisms. This comprehensive systematic review and meta-analysis aimed to evaluate and compare the safety and effectiveness of antireflux therapy during endoscopic cardia peripheral tissue scar formation (ECSF) procedures. We comprehensively searched the Web of Science, PubMed, Embase, China National Knowledge Infrastructure, and Wan-Fang databases for articles published from January 1990 to January 2024. Network meta-analysis (NMA) was used to assess the outcomes, with outcome metrics including the Gastroesophageal Reflux Questionnaire (GERD-Q) score, proton pump inhibitor discontinuation rate, pH
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0311208