Design and implementation of corrosion-resistant multitasking cell stainers

Compared with machine staining, traditional manual staining faces various problems, such as a low preparation success rate, low efficiency, and harm to the human body due to corrosive gases. Therefore, a stainer that is of low cost, has strong corrosion resistance, and is suitable for small-batch pr...

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Veröffentlicht in:PloS one 2024-10, Vol.19 (10), p.e0309334
Hauptverfasser: Liao, Chengsheng, Gong, Zhen, Fang, Run, Li, Leheng, Gao, Zhifan, Mao, Min, Zeng, Libo
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container_start_page e0309334
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creator Liao, Chengsheng
Gong, Zhen
Fang, Run
Li, Leheng
Gao, Zhifan
Mao, Min
Zeng, Libo
description Compared with machine staining, traditional manual staining faces various problems, such as a low preparation success rate, low efficiency, and harm to the human body due to corrosive gases. Therefore, a stainer that is of low cost, has strong corrosion resistance, and is suitable for small-batch preparation should be developed. In this study, by choosing a rotary scheme as the structural basis, a reusable container cover and a master-slave manipulator cooperation scheme are developed, which greatly improve the space utilization rate. Through material selection and structural design, in the designed stainer, effective protection against strong acids with high volatility and permeability is realized, thereby eliminating the corrosion issue. Using the designed splitting-running algorithm for the dyeing procedure, simultaneous multistaining is realized, which significantly improves the staining efficiency. Compared with large-sized stainers, the cost of the proposed stainer is very low, which will help popularize early screening for cervical cancer in low- and middle-income countries.
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subjects Algorithms
Biology and Life Sciences
Care and treatment
Cellular biology
Cervical cancer
Coloring Agents - chemistry
Cooperation
Corrosion
Corrosion cell
Corrosion prevention
Corrosion rate
Corrosion resistance
Corrosion tests
Cytodiagnosis
Design
Diagnosis
Dyes
Engineering and Technology
Equipment Design
Evaluation
Gases
Human papillomavirus
Humans
Laboratories
Liquor
Low income groups
Materials selection
Medicine and Health Sciences
Multitasking
Physical Sciences
Pyrrhocoridae
Research and Analysis Methods
Staining
Staining and Labeling - methods
Structural design
Structural engineering
title Design and implementation of corrosion-resistant multitasking cell stainers
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