The impact of biologic agents on cardiovascular risk factors in patients with rheumatoid arthritis: A meta analysis

The purpose of the study is to evaluate the effects of biologic therapy on cardiovascular risk factors in rheumatoid arthritis patients to determine its clinical efficacy. Relevant literature was systematically searched in PubMed, Embase, and Cochrane Library databases. Meta-analysis was conducted u...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2024-08, Vol.19 (8), p.e0306513
Hauptverfasser:	Jia, Xiaodong, Yang, Zheming, Li, Jiayin, Mei, Zhu, Jia, Lihui, Yan, Chenghui
Format:	Artikel
Sprache:	eng
Schlagworte:	Antirheumatic Agents - therapeutic use Arteriosclerosis Arthritis Arthritis, Rheumatoid - complications Arthritis, Rheumatoid - drug therapy Atherosclerosis Autoimmune diseases Bias Biological effects Biological Factors - therapeutic use Biological products Biological treatment Biology and Life Sciences Cardiovascular diseases Cardiovascular Diseases - etiology Carotid arteries Carotid artery Chi-square test Cholesterol Cholesterol, HDL - blood Complications and side effects Cytokines Density Disease Drug therapy Health aspects Health risks Heart Disease Risk Factors Heterogeneity High density lipoprotein Humans Immunosuppressive agents Impact analysis Inflammation Keywords Lipid metabolism Lipids Low density lipoprotein Medicine and Health Sciences Meta-analysis Patients Physical Sciences Prevention Research and Analysis Methods Rheumatoid arthritis Risk Factors Sensitivity analysis Side effects Statistical analysis Subgroups Therapy Triglycerides Tumor necrosis factor-TNF Wave velocity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The purpose of the study is to evaluate the effects of biologic therapy on cardiovascular risk factors in rheumatoid arthritis patients to determine its clinical efficacy. Relevant literature was systematically searched in PubMed, Embase, and Cochrane Library databases. Meta-analysis was conducted using standardized mean differences (SMDs) and 95% confidence intervals (CIs) to evaluate cardiovascular risk factors and atherosclerosis. Heterogeneity, sensitivity analysis, and publication bias were assessed. Statistical significance was set at P
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0306513