Diagnosis of tuberculosis infection in children with a novel skin test and the traditional tuberculin skin test: An observational study

A novel skin test-called Diaskintest (DT)-containing specific M. tuberculosis antigens is in clinical use in the Russian Federation (RF). This test may improve diagnosis of tuberculosis (TB) infection. The use and performance of the DT was described and compared to the tuberculin skin test (TST). Da...

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Veröffentlicht in:	PloS one 2024-08, Vol.19 (8), p.e0293272
Hauptverfasser:	Fritschi, Nora, Gureva, Tatyana, Eliseev, Platon, Jackson, Charlotte, Milanzi, Edith, Crichton, Siobhan, Collins, Intira Jeannie, Turkova, Anna, Mariandyshev, Andrei, Ritz, Nicole
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Agreements Analysis Antigens Antigens, Bacterial - analysis Antigens, Bacterial - immunology Antitubercular agents BCG Vaccine - immunology Child Child, Preschool Children Clinics Demographic aspects Diagnosis Dosage and administration Drug therapy Ethics Female Health aspects Humans Immunization Immunology Infant Infections Male Medical diagnosis Medicine and Health Sciences Meta-analysis Mycobacterium tuberculosis - immunology Observational studies Patient outcomes Patients Pediatrics People and Places Primary care Skin Skin diseases Skin tests Skin Tests - methods Teenagers Tuberculin Tuberculin test Tuberculin Test - methods Tuberculosis Tuberculosis - diagnosis Vaccination Vaccines
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Zusammenfassung:	A novel skin test-called Diaskintest (DT)-containing specific M. tuberculosis antigens is in clinical use in the Russian Federation (RF). This test may improve diagnosis of tuberculosis (TB) infection. The use and performance of the DT was described and compared to the tuberculin skin test (TST). Data on children
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0293272