A conserved switch controls virulence, sporulation, and motility in C. difficile

Spore formation is required for environmental survival and transmission of the human enteropathogenic Clostridioides difficile. In all bacterial spore formers, sporulation is regulated through activation of the master response regulator, Spo0A. However, the factors and mechanisms that directly regul...

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Veröffentlicht in:PLoS pathogens 2024-05, Vol.20 (5), p.e1012224-e1012224
Hauptverfasser: DiCandia, Michael A, Edwards, Adrianne N, Alcaraz, Ysabella B, Monteiro, Marcos P, Lee, Cheyenne D, Vargas Cuebas, Germán, Bagchi, Pritha, McBride, Shonna M
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Sprache:eng
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