Multiple checkpoints ensure ribosomes have the correct end

Multiple checkpoints ensure ribosomes have the correct end

The 3′ end of the 18S ribosomal RNA is formed by the endoribonuclease Nob1. How cells ensure the accuracy of the 3′ end has remained a mystery. A new study in PLOS Biology revealed that there are multiple checkpoints to ensure that only ribosomes containing the correct 3′ end participate in translat...

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Veröffentlicht in:PLoS biology 2024-04, Vol.22 (4), p.e3002603
Hauptverfasser: Gordon, Jacob, Stanley, Robin E
Format: Artikel
Sprache:eng
Schlagworte:
Biology and Life Sciences
Engineering and Technology
Physiological aspects
Primer
Quality control
Research and Analysis Methods
Ribonucleic acid
Ribosomes
RNA
rRNA 18S
Yeast
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Zusammenfassung:The 3′ end of the 18S ribosomal RNA is formed by the endoribonuclease Nob1. How cells ensure the accuracy of the 3′ end has remained a mystery. A new study in PLOS Biology revealed that there are multiple checkpoints to ensure that only ribosomes containing the correct 3′ end participate in translation.
ISSN:1545-7885
1544-9173
1545-7885
DOI:10.1371/journal.pbio.3002603