The changing characteristics of a cohort of children and adolescents living with HIV at antiretroviral therapy initiation in Asia

Despite improvements in HIV testing and earlier antiretroviral therapy (ART) initiation in children living with HIV through the years, a considerable proportion start treatment with advanced disease. We studied characteristics of children and adolescents living with HIV and their level of immunodefi...

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Veröffentlicht in:	PloS one 2023-09, Vol.18 (9), p.e0291523
Hauptverfasser:	Sornillo, Johanna Beulah, Ditangco, Rossana, Kinikar, Aarti, Wati, Dewi Kumara, Du, Quy Tuan, Nguyen, Dinh Qui, Khol, Vohith, Nguyen, Lam Van, Puthanakit, Thanyawee, Ounchanum, Pradthana, Kurniati, Nia, Chokephaibulkit, Kulkanya, Jamal Mohamed, Thahira A, Sudjaritruk, Tavitiya, Fong, Siew Moy, Kumarasamy, Nagalingeswaran, Kosalaraksa, Pope, Nallusamy, Revathy A, Nik Yusoff, Nik Khairulddin, Sohn, Annette H, Kariminia, Azar
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adolescent Adolescents Age AIDS Ambulatory Care Analysis Anti-Retroviral Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Antiviral agents Asia - epidemiology Biology and Life Sciences CD4 antigen Child Child, Preschool Children Drug therapy Evidence-based medicine Female Health aspects Highly active antiretroviral therapy HIV HIV (Viruses) HIV infection in children HIV Infections - drug therapy HIV Infections - epidemiology HIV patients HIV testing Human immunodeficiency virus Humans Immune system Immunodeficiency Male Medical diagnosis Medical records Medical research Medicine and Health Sciences Medicine, Experimental Missing data Opportunistic Infections Patient outcomes Patients Pediatrics People and Places Regression analysis Risk analysis Risk factors Statistics Teenagers
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Zusammenfassung:	Despite improvements in HIV testing and earlier antiretroviral therapy (ART) initiation in children living with HIV through the years, a considerable proportion start treatment with advanced disease. We studied characteristics of children and adolescents living with HIV and their level of immunodeficiency at ART initiation using data from a multi-country Asian cohort. We included children and adolescents who were ART-naïve and
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0291523