A broadly neutralizing monoclonal antibody overcomes the mutational landscape of emerging SARS-CoV-2 variants of concern

The emergence of new variants of SARS-CoV-2 necessitates unremitting efforts to discover novel therapeutic monoclonal antibodies (mAbs). Here, we report an extremely potent mAb named P4A2 that can neutralize all the circulating variants of concern (VOCs) with high efficiency, including the highly tr...

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Veröffentlicht in:PLoS pathogens 2022-12, Vol.18 (12), p.e1010994
Hauptverfasser: Parray, Hilal Ahmad, Narayanan, Naveen, Garg, Sonal, Rizvi, Zaigham Abbas, Shrivastava, Tripti, Kushwaha, Sachin, Singh, Janmejay, Murugavelu, Praveenkumar, Anantharaj, Anbalagan, Mehdi, Farha, Raj, Nisha, Singh, Shivam, Dandotiya, Jyotsna, Lukose, Asha, Jamwal, Deepti, Kumar, Sandeep, Chiranjivi, Adarsh K, Dhyani, Samridhi, Mishra, Nitesh, Kumar, Sanjeev, Jakhar, Kamini, Sonar, Sudipta, Panchal, Anil Kumar, Tripathy, Manas Ranjan, Chowdhury, Shirlie Roy, Ahmed, Shubbir, Samal, Sweety, Mani, Shailendra, Bhattacharyya, Sankar, Das, Supratik, Sinha, Subrata, Luthra, Kalpana, Batra, Gaurav, Sehgal, Devinder, Medigeshi, Guruprasad R, Sharma, Chandresh, Awasthi, Amit, Garg, Pramod Kumar, Nair, Deepak T, Kumar, Rajesh
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Sprache:eng
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