Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view
We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects includ...
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| Veröffentlicht in: | PloS one 2022-12, Vol.17 (12), p.e0278679-e0278679 |
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| creator | Motschi, Alice R Schwarzhans, Florian Desissaire, Sylvia Steiner, Stefan Bogunović, Hrvoje Roberts, Philipp K Vass, Clemens Hitzenberger, Christoph K Pircher, Michael |
| description | We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated. |
| doi_str_mv | 10.1371/journal.pone.0278679 |
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A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0278679</identifier><identifier>PMID: 36512582</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Age ; Biology and Life Sciences ; Care and treatment ; Datasets ; Depolarization ; Diagnosis ; Epithelium ; Field of view ; Fluorescein Angiography - methods ; Glaucoma ; Health aspects ; Health Status ; Humans ; Medicine and Health Sciences ; Photoreceptors ; Physical Sciences ; Refraction, Ocular ; Retina ; Retinal pigment epithelium ; Retinal Pigment Epithelium - diagnostic imaging ; Social Sciences ; Spatial analysis ; Spatial distribution ; Tomography, Optical Coherence - methods ; Visual field</subject><ispartof>PloS one, 2022-12, Vol.17 (12), p.e0278679-e0278679</ispartof><rights>Copyright: © 2022 Motschi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2022 Public Library of Science</rights><rights>2022 Motschi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 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A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.</description><subject>Age</subject><subject>Biology and Life Sciences</subject><subject>Care and treatment</subject><subject>Datasets</subject><subject>Depolarization</subject><subject>Diagnosis</subject><subject>Epithelium</subject><subject>Field of view</subject><subject>Fluorescein Angiography - methods</subject><subject>Glaucoma</subject><subject>Health aspects</subject><subject>Health Status</subject><subject>Humans</subject><subject>Medicine and Health Sciences</subject><subject>Photoreceptors</subject><subject>Physical Sciences</subject><subject>Refraction, Ocular</subject><subject>Retina</subject><subject>Retinal pigment epithelium</subject><subject>Retinal Pigment Epithelium - diagnostic imaging</subject><subject>Social Sciences</subject><subject>Spatial analysis</subject><subject>Spatial distribution</subject><subject>Tomography, Optical Coherence - methods</subject><subject>Visual 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assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view</title><author>Motschi, Alice R ; Schwarzhans, Florian ; Desissaire, Sylvia ; Steiner, Stefan ; Bogunović, Hrvoje ; Roberts, Philipp K ; Vass, Clemens ; Hitzenberger, Christoph K ; Pircher, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-304f30aefe532af52ea8271217fa176047ad2776629c54c1bfa50c634f2a0c133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Age</topic><topic>Biology and Life Sciences</topic><topic>Care and treatment</topic><topic>Datasets</topic><topic>Depolarization</topic><topic>Diagnosis</topic><topic>Epithelium</topic><topic>Field of view</topic><topic>Fluorescein Angiography - methods</topic><topic>Glaucoma</topic><topic>Health aspects</topic><topic>Health Status</topic><topic>Humans</topic><topic>Medicine and 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A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>36512582</pmid><doi>10.1371/journal.pone.0278679</doi><tpages>e0278679</tpages><orcidid>https://orcid.org/0000-0003-4756-9088</orcidid><orcidid>https://orcid.org/0000-0003-0804-2304</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Age Biology and Life Sciences Care and treatment Datasets Depolarization Diagnosis Epithelium Field of view Fluorescein Angiography - methods Glaucoma Health aspects Health Status Humans Medicine and Health Sciences Photoreceptors Physical Sciences Refraction, Ocular Retina Retinal pigment epithelium Retinal Pigment Epithelium - diagnostic imaging Social Sciences Spatial analysis Spatial distribution Tomography, Optical Coherence - methods Visual field |
| title | Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view |
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