Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view

We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects includ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2022-12, Vol.17 (12), p.e0278679-e0278679
Hauptverfasser:	Motschi, Alice R, Schwarzhans, Florian, Desissaire, Sylvia, Steiner, Stefan, Bogunović, Hrvoje, Roberts, Philipp K, Vass, Clemens, Hitzenberger, Christoph K, Pircher, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Biology and Life Sciences Care and treatment Datasets Depolarization Diagnosis Epithelium Field of view Fluorescein Angiography - methods Glaucoma Health aspects Health Status Humans Medicine and Health Sciences Photoreceptors Physical Sciences Refraction, Ocular Retina Retinal pigment epithelium Retinal Pigment Epithelium - diagnostic imaging Social Sciences Spatial analysis Spatial distribution Tomography, Optical Coherence - methods Visual field
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0278679