Awakening dormant neurons long after spinal cord injury

Neurons lack the ability to regenerate after injury. A new Preregistered Article in PLOS Biology finds that pharmacologically boosting regenerative capacity long after injury in mice, together with an enriched animal environment, promotes axonal and synaptic plasticity.

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Bibliographische Detailangaben
Veröffentlicht in:	PLoS biology 2022-09, Vol.20 (9), p.e3001830-e3001830
Hauptverfasser:	Tapia, Mary L, Park, Kevin K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axonal plasticity Biology and Life Sciences Epigenetics Gene expression Life expectancy Medicine and Health Sciences Nervous system Neurons Primer Spinal cord injuries Synaptic plasticity
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Neurons lack the ability to regenerate after injury. A new Preregistered Article in PLOS Biology finds that pharmacologically boosting regenerative capacity long after injury in mice, together with an enriched animal environment, promotes axonal and synaptic plasticity.
ISSN:	1545-7885 1544-9173 1545-7885
DOI:	10.1371/journal.pbio.3001830