Malignant neoplasms in people with hypothyroidism in Spain: A population-based analysis

Malignant neoplasms in people with hypothyroidism in Spain: A population-based analysis

The objective of this study was to determine the association between hypothyroidism and overall and site-specific cancer in Spanish population. A cross-sectional study was performed using the population-based database BDCAP (Base de Datos Clínicos de Atención Primaria, primary care clinical database...

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Veröffentlicht in:PloS one 2022-10, Vol.17 (10), p.e0275568
Hauptverfasser: Díez, Juan J, Iglesias, Pedro
Format: Artikel
Sprache:eng
Schlagworte:
Bladder cancer
Breast cancer
Cancer
Cancer therapies
Care and treatment
Colorectal cancer
Complications and side effects
Country of birth
Cross-Sectional Studies
Female
Gastric cancer
Gene expression
Health care
Health risks
Hormone Replacement Therapy
Humans
Hypothyroidism
Hypothyroidism - complications
Hypothyroidism - diagnosis
Hypothyroidism - epidemiology
Male
Medical records
Medicine and Health Sciences
Mortality
Neoplasms
Neoplasms - complications
Neoplasms - drug therapy
Neoplasms - epidemiology
Patients
Population
Population studies
Prevention
Primary care
Prostate
Prostate cancer
Risk factors
Risk management
Risk reduction
Spain - epidemiology
Thyroid cancer
Thyroid gland
Tumors
Variables
Womens health
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Beschreibung
Zusammenfassung:The objective of this study was to determine the association between hypothyroidism and overall and site-specific cancer in Spanish population. A cross-sectional study was performed using the population-based database BDCAP (Base de Datos Clínicos de Atención Primaria, primary care clinical database) to analyze the relative risk of cancer in Spanish population with hypothyroidism. In a total of 2,414,165 patients diagnosed with hypothyroidism in BDCAP in 2019, the relative risk (OR) of cancer, compared to the non-hypothyroid population, was 1.73 (1.72-1.74) (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0275568