Effectiveness of shengxuexiaoban capsules combined with glucocorticoid therapy for immune thrombocytopenia: A meta-analysis

To evaluate the effectiveness of the Shengxuexiaoban Capsules combined with glucocorticoid therapy for immune thrombocytopenia (ITP). We collected randomized controlled trials (RCTs) using shengxuexiaoban capsules in combination with glucocorticoid to treat ITP by searching major Chinese and English...

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Veröffentlicht in:	PloS one 2022-09, Vol.17 (9), p.e0275122-e0275122
Hauptverfasser:	Ding, Meng-Yuan, Li, Bing, Yang, Meng, Zhai, Wen-Sheng, Song, Chun-Dong, Zhang, Jian, Zhang, Qiu-Yue, Li, Peng-Fei, Liu, Li-Ya
Format:	Artikel
Sprache:	eng
Schlagworte:	Bias Biology and Life Sciences Blood platelets Care and treatment Clinical trials Complications and side effects Effectiveness Glucocorticoids Idiopathic thrombocytopenic purpura Medical research Medicine and Health Sciences Medicine, Chinese Meta-analysis Patient outcomes Performance evaluation Physical Sciences Platelets Purpura Quality assessment Recovery time Research and Analysis Methods Therapy Thrombocytopenia
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Beschreibung
Zusammenfassung:	To evaluate the effectiveness of the Shengxuexiaoban Capsules combined with glucocorticoid therapy for immune thrombocytopenia (ITP). We collected randomized controlled trials (RCTs) using shengxuexiaoban capsules in combination with glucocorticoid to treat ITP by searching major Chinese and English electronic databases. The outcome indicators were the effective rate, recurrence rate, the number of platelets in the blood, recovery time of platelets, and adverse reactions. We used STATA 16.0 and RevMan 5.3 for meta-analysis and GRADE pro. for evidence quality evaluation. A total of 27 RCTs were included in the meta-analysis, and the results showed a significant difference (all p
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0275122