Impact of ultrasonographic blind spots for early-stage hepatocellular carcinoma during surveillance

Impact of ultrasonographic blind spots for early-stage hepatocellular carcinoma during surveillance

Abdominal ultrasonography (US) is the backbone of hepatocellular carcinoma (HCC) surveillance. Although previous studies have evaluated clinical factors related to surveillance failure, none have focused specifically on US blind spots. This study included 1,289 patients who underwent 6 months interv...

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Veröffentlicht in:PloS one 2022-09, Vol.17 (9), p.e0274747-e0274747
Hauptverfasser: Lee, Junghwan, Park, Su Bee, Byun, Soyoung, Kim, Ha Il
Format: Artikel
Sprache:eng
Schlagworte:
Ablation
Biology and life sciences
Care and treatment
Diagnosis
Evaluation
Health services
Hepatitis
Hepatocellular carcinoma
Hepatoma
Hospitals
Hypertension
Infections
Liver cancer
Liver cirrhosis
Liver diseases
Magnetic resonance imaging
Medical prognosis
Medicine and Health Sciences
Patients
Research and Analysis Methods
Review boards
Surveillance
Survival
Tumors
Ultrasonic imaging
Ultrasound imaging
α-Fetoprotein
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Zusammenfassung:Abdominal ultrasonography (US) is the backbone of hepatocellular carcinoma (HCC) surveillance. Although previous studies have evaluated clinical factors related to surveillance failure, none have focused specifically on US blind spots. This study included 1,289 patients who underwent 6 months intervals surveillance using US and serum alpha-fetoprotein (AFP) and were eventually diagnosed with single-nodular HCC. Patients were divided into US-detected group (n = 1,062) and US-missed group (HCC detected only by AFP [greater than or equal to] 20ng/mL; n = 227). Blind spots consisted of four locations: hepatic dome, caudate lobe or around the inferior vena cava,
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0274747