Age-related twin-peak prevalence profiles of H. pylori infection, gastritis, GIN and gastric cancer: Analyses of 70,534 patients with gastroscopic biopsies

Age-related twin-peak prevalence profiles of H. pylori infection, gastritis, GIN and gastric cancer: Analyses of 70,534 patients with gastroscopic biopsies

H. pylori (Hp) infection has been indicated in the pathogenesis of gastric diseases including gastric cancer (GC). This study aimed at exploring the relationships between Hp infection and gastric diseases including GC in a large dataset of routine patients undergoing gastroscopy. From November 2007...

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Veröffentlicht in:PloS one 2022-07, Vol.17 (7), p.e0265885-e0265885
Hauptverfasser: Xu, Meng Qing, Sun, Ke, Cao, Chong, Yin, Hui Hui, Wang, Xiao Jun, Yin, Qi Hang, Wang, Li Jie, Tao, Lin, Wang, Kui, Li, Feng, Zhang, Wen Jie
Format: Artikel
Sprache:eng
Schlagworte:
Age
Biology and Life Sciences
Biopsy
Cancer
Complications and side effects
Demographic aspects
Diagnosis
Diseases
Distribution
Females
Gastric cancer
Gastritis
Gastroscopy
Helicobacter infections
Helicobacter pylori
Infections
Males
Medicine and Health Sciences
Pathogenesis
Stomach cancer
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Zusammenfassung:H. pylori (Hp) infection has been indicated in the pathogenesis of gastric diseases including gastric cancer (GC). This study aimed at exploring the relationships between Hp infection and gastric diseases including GC in a large dataset of routine patients undergoing gastroscopy. From November 2007 to December 2017, 70,534 first-time visiting patients aged 18-94 years with gastroscopic biopsies were histologically diagnosed and analyzed. Patients' data were entered twice in an Excel spreadsheet database and analyzed using the SPSS (version 22.0) software package and statistical significance was defined as P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0265885