Increase in short telomeres during the third trimester in human placenta
An increase in telomere shortening in gestational tissues has been proposed as a mechanism involved in the timing for the initiation of parturition. An increase in very short telomeres with increasing gestational age has been observed in mice; this study sought to explore this phenomenon in human pr...
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Veröffentlicht in: | PloS one 2022-07, Vol.17 (7), p.e0271415-e0271415 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | An increase in telomere shortening in gestational tissues has been proposed as a mechanism involved in the timing for the initiation of parturition. An increase in very short telomeres with increasing gestational age has been observed in mice; this study sought to explore this phenomenon in human pregnancies. Specifically, this study addressed the hypothesis that prior to labor, the quantity of very short telomeres ( |
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ISSN: | 1932-6203 1932-6203 |
DOI: | 10.1371/journal.pone.0271415 |