Gender based lung cancer risks for symptomatic coronary artery disease patients undergone cardiac CT

We estimate the lifetime attributable risk (LAR) of lung cancer incidence in symptomatic Coronary Artery Disease (CAD) patients receiving enhanced Coronary Computed Tomography Angiography (CCTA) and the unenhanced Computed Tomography Calcium Scoring (CTCS) examination. Retrospective analysis has bee...

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Veröffentlicht in:PloS one 2022-04, Vol.17 (4), p.e0265609-e0265609
Hauptverfasser: Dalah, Entesar Zawam, Obaideen, Abdulmunhem, Anam, Sabaa, Alzimami, Khalid, Jambi, Layal Khalid, Bradley, David A
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Sprache:eng
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Zusammenfassung:We estimate the lifetime attributable risk (LAR) of lung cancer incidence in symptomatic Coronary Artery Disease (CAD) patients receiving enhanced Coronary Computed Tomography Angiography (CCTA) and the unenhanced Computed Tomography Calcium Scoring (CTCS) examination. Retrospective analysis has been made of CCTA and CTCS data collected for 87 confirmed CAD adult patients. Patient effective dose (E) and organ doses (ODs) were calculated using CT-EXPO. Statistical correlation and the differences between E and ODs in enhanced CCTA and unenhanced CTCS were calculated using the Pearson coefficient and Wilcoxon unpaired t-test. Following BEIR VII report guidance, organ-specific LARs for the cohort were estimated using the organ-equivalent dose-to-risk conversion factor for numbers of cases per 100,000 patients exposed to low doses of 0.1 Gy. Significant statistical difference (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0265609