Chorioallantoic membrane (CAM) assay to study treatment effects in diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain tumor. While there are a number of in vivo rodent models for evaluating tumor biology and response to therapy, these models require significant time and resources. Here, we established the chick-embryo chorioallantoic (CAM) assay as...

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Veröffentlicht in:	PloS one 2022-02, Vol.17 (2), p.e0263822-e0263822
Hauptverfasser:	Power, Erica A, Fernandez-Torres, Jenelys, Zhang, Liang, Yaun, Ruiyi, Lucien, Fabrice, Daniels, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - pharmacology Angiogenesis Inhibitors - therapeutic use Animal models Animal models in research Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Auroral kilometric radiation Biology and Life Sciences Brain cancer Brain Stem Neoplasms - drug therapy Brain Stem Neoplasms - genetics Brain Stem Neoplasms - pathology Brain Stem Neoplasms - radiotherapy Brain tumors Cancer Cancer therapies Care and treatment Cell Line, Tumor Chick Embryo Chorioallantoic membrane Chorioallantoic Membrane - drug effects Chorioallantoic Membrane - pathology Chorioallantoic Membrane - radiation effects Diffuse Intrinsic Pontine Glioma - drug therapy Diffuse Intrinsic Pontine Glioma - genetics Diffuse Intrinsic Pontine Glioma - pathology Diffuse Intrinsic Pontine Glioma - radiotherapy Drug therapy Embryos Epigenetics Fetal membranes Genetic aspects Glioma Gliomas Health aspects Humans In vivo methods and tests Laboratory animals Medicine and Health Sciences Methods Model testing Modelling Mutation Oncology, Experimental Pediatrics Pharmacology Radiation Radiation therapy Rats Surgery Treatment outcome Tumors Ultrasonic imaging Ultrasonography Xenograft Model Antitumor Assays Xenografts Xenotransplantation
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