Blocking HTLV-1/2 silent transmission in Brazil: Current public health policies and proposal for additional strategies

Human T-cell lymphotropic viruses 1 and 2 (HTLV-1/2) are relatively common in Brazil but remain silent and neglected infections. HTLV-1 is associated with a range of diseases with high morbidity and mortality. There is no curative treatment for this lifelong infection, so measures to prevent transmi...

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Veröffentlicht in:	PLoS neglected tropical diseases 2021-09, Vol.15 (9), p.e0009717
Hauptverfasser:	Rosadas, Carolina, Menezes, Maria Luiza B, Galvão-Castro, Bernardo, Assone, Tatiane, Miranda, Angélica E, Aragón, Mayra G, Caterino-de-Araujo, Adele, Taylor, Graham P, Ishak, Ricardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Asymptomatic Biology and life sciences Blood & organ donations Blood-borne diseases Brazil - epidemiology Control Couples Disease transmission Health Policy HTLV infections HTLV-I Infections - epidemiology HTLV-I Infections - transmission HTLV-I Infections - virology HTLV-II Infections - epidemiology HTLV-II Infections - transmission HTLV-II Infections - virology Human T-lymphotropic virus 1 - genetics Human T-lymphotropic virus 1 - physiology Human T-lymphotropic virus 2 - genetics Human T-lymphotropic virus 2 - physiology Humans Infections Laws, regulations and rules Lymphocytes T Medical policy Medicine and Health Sciences Morbidity Mortality People and places Perinatal infection Policies Prevention Public health Public Policy Quality of life Review Risk factors Sexual intercourse Sexually transmitted diseases Social Sciences Sperm Transmission Tropical diseases Vagina Viruses
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Beschreibung
Zusammenfassung:	Human T-cell lymphotropic viruses 1 and 2 (HTLV-1/2) are relatively common in Brazil but remain silent and neglected infections. HTLV-1 is associated with a range of diseases with high morbidity and mortality. There is no curative treatment for this lifelong infection, so measures to prevent transmission are essential. This narrative review discusses HTLV-1/2 transmission routes and measures to prevent its continuous dissemination. The public health policies that are currently implemented in Brazil to avoid HTLV-1/2 transmission are addressed, and further strategies are proposed.
ISSN:	1935-2735 1935-2727 1935-2735
DOI:	10.1371/journal.pntd.0009717