Mortality and associated risk factors of COVID-19 infection in dialysis patients in Qatar: A nationwide cohort study

Context Patients on maintenance dialysis are more susceptible to COVID-19 and its severe form. We studied the mortality and associated risks of COVID-19 infection in dialysis patients in the state of Qatar. Methods This was an observational, analytical, retrospective, nationwide study. We included a...

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Veröffentlicht in:PloS one 2021-07, Vol.16 (7), p.e0254246-e0254246
Hauptverfasser: Ghonimi, Tarek Abdel Latif, Alkad, Mohamad Mahmood, Abuhelaiqa, Essa Abdulla, Othman, Muftah M., Elgaali, Musab Ahmed, Ibrahim, Rania Abdelaziz M., Joseph, Shajahan M., Al-Malki, Hassan Ali, Hamad, Abdullah Ibrahim
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Sprache:eng
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Zusammenfassung:Context Patients on maintenance dialysis are more susceptible to COVID-19 and its severe form. We studied the mortality and associated risks of COVID-19 infection in dialysis patients in the state of Qatar. Methods This was an observational, analytical, retrospective, nationwide study. We included all adult patients on maintenance dialysis therapy who tested positive for COVID-19 (PCR assay of the nasopharyngeal swab) during the period from February 1, 2020, to July 19, 2020. Our primary outcome was to study the mortality of COVID-19 in dialysis patients in Qatar and risk factors associated with it. Our secondary objectives were to study incidence and severity of COVID-19 in dialysis patients and comparing outcomes between hemodialysis and peritoneal dialysis patients. Patient demographics and clinical features were collected from a national electronic medical record. Univariate Cox regression analysis was performed to evaluate potential risk factors for mortality in our cohort. Results 76 out of 1064 dialysis patients were diagnosed with COVID-19 (age 56±13.6, 56 hemodialysis and 20 peritoneal dialysis, 56 males). During the study period, 7.1% of all dialysis patients contracted COVID-19. Male dialysis patients had double the incidence of COVID-19 than females (9% versus 4.5% respectively; p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0254246