Anti-inflammatory, antibacterial and immunomodulatory treatment in children with symptoms corresponding to the research condition PANS (Pediatric Acute-onset Neuropsychiatric Syndrome): A systematic review

To assess effects of treatment against a hypothesized neuroinflammation in children with symptoms corresponding to the research condition Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) which is not included in current diagnostic systems. Systematic literature searches were performed (1998 to...

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Veröffentlicht in:	PloS one 2021-07, Vol.16 (7), p.e0253844
Hauptverfasser:	Johnson, Mats, Ehlers, Stephan, Fernell, Elisabeth, Hajjari, Parisa, Wartenberg, Constanze, Wallerstedt, Susanna M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - adverse effects Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - adverse effects Anti-inflammatory drugs Antibacterial agents Antibiotics Antiinfectives and antibacterials Autoimmune Diseases - immunology Autoimmune Diseases - therapy Azithromycin Bias Biology and Life Sciences Care and treatment Child Children Clinical trials Combined Modality Therapy - adverse effects Combined Modality Therapy - methods Complications Complications and side effects Corticoids Corticosteroids Diagnostic systems Diseases disorders Glucocorticoids - administration & dosage Glucocorticoids - adverse effects Health risks Health services Hospitals Humans Immunoglobulins Immunoglobulins, Intravenous - administration & dosage Immunoglobulins, Intravenous - adverse effects Immunologic Factors - administration & dosage Immunologic Factors - adverse effects Immunomodulation Inflammation Intervention Intravenous administration intravenous immunoglobulin Literature reviews Medical research Medicine and Health Sciences Mental disorders Obsessive compulsive disorder Obsessive-Compulsive Disorder - immunology Obsessive-Compulsive Disorder - therapy Patient outcomes Patients Pediatrics Penicillin Penicillin V Plasma Exchange - adverse effects Plasma Exchange - methods Population studies prophylaxis Prostaglandin endoperoxide synthase Psychiatry Psykiatri Quality of Life R&D Randomized Controlled Trials as Topic Research & development Research and Analysis Methods Science & Technology - Other Topics Side effects Software reviews streptococcal infections Systematic review TNF inhibitors Treatment Outcome Tumor necrosis factor-TNF youth
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