Blood coagulation parameter abnormalities in hospitalized patients with confirmed COVID-19 in Ethiopia

Blood coagulation parameter abnormalities in hospitalized patients with confirmed COVID-19 in Ethiopia

Coagulopathy and thromboembolic events are among the complications of Corona Virus disease 2019 (COVID-19). Abnormal coagulation parameters in COVID-19 patients are important prognostic factors of disease severity. The aim of this study was to analyze coagulation profiles of hospitalized COVID-19 pa...

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Veröffentlicht in:PloS one 2021-06, Vol.16 (6), p.e0252939-e0252939
Hauptverfasser: Araya, Shambel, Mamo, Mintesnot Aragaw, Tsegay, Yakob Gebregziabher, Atlaw, Asegdew, Aytenew, Aschalew, Hordofa, Abebe, Negeso, Abebe Edao, Wordofa, Moges, Niguse, Tirhas, Cheru, Mahlet, Tamir, Zemenu
Format: Artikel
Sprache:eng
Schlagworte:
Abnormalities
Biology and Life Sciences
Biotechnology
Blood
Blood clotting
Blood coagulation
Coagulation
Computer programs
Corona
Coronaviruses
COVID-19
Data analysis
Drafting software
Editing
Ethics
Funding
Health sciences
Health services
Infections
Medical laboratories
Medical prognosis
Medical research
Medical schools
Medicine and Health Sciences
Methodology
Parameters
Patients
People and Places
Polymerase chain reaction
R&D
Research & development
Research ethics
Respiratory distress syndrome
Risk factors
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Sociodemographics
Software
Statistical analysis
Supervision
Values
Viral diseases
Viruses
Visualization
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Zusammenfassung:Coagulopathy and thromboembolic events are among the complications of Corona Virus disease 2019 (COVID-19). Abnormal coagulation parameters in COVID-19 patients are important prognostic factors of disease severity. The aim of this study was to analyze coagulation profiles of hospitalized COVID-19 patients in Addis Ababa, Ethiopia. This prospective cross-sectional study was conducted among 455 Covid-19 patients admitted at Millennium COVID-19 care and treatment center, Addis Ababa, Ethiopia from July 1- October 23, 2020. Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT) and International normalized ratio (INR) were determined on HUMACLOT DUE PLUS® coagulation analyzer (Wiesbaden, Germany). In all statistical analysis of results, p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0252939