LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr 1, encoding a small regulatory RNA

QS depends on the production, release, and detection of signal molecules called autoinducers (AIs). Because AIs are self-produced by the bacteria, as cell density increases, extracellular AI levels likewise increase. Dephosphorylated LuxO is inactive. [...]Qrr1-5 are not produced, aphA translation is not activated, and luxR translation is not repressed (Fig 1B). Qrr2-5 regulate an identical set of target mRNAs [30]. [...]the failure of Qrr1 to control one subset of mRNAs is the only functional difference known among the Qrr sRNAs. [...]we show that LuxT repression of qrr1 transcription is not specific to V. harveyi.