Clinical significance of potential drug-drug interactions in a pediatric intensive care unit: A single-center retrospective study

Despite the high prevalence of potential drug-drug interactions in pediatric intensive care units, their clinical relevance and significance are unclear. We assessed the characteristics and risk factors of clinically relevant potential drug-drug interactions to facilitate their efficient monitoring...

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Veröffentlicht in:	PloS one 2021-02, Vol.16 (2), p.e0246754
Hauptverfasser:	Choi, Yu Hyeon, Lee, In Hwa, Yang, Mihee, Cho, Yoon Sook, Jo, Yun Hee, Bae, Hye Jung, Kim, You Sun, Park, June Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Algorithms Causality Child Child, Preschool Clinical significance Complexity Contraindications Data collection Demographic aspects Demographics Demography Documentation Drug dosages Drug Interactions Drug Monitoring Drug stores Drug therapy Electronic health records Electronic medical records Female Flow charts Forecasts and trends Health risks Hospitals Humans Infant Infant, Newborn Intensive care Intensive Care Units, Pediatric Length of Stay Male Medicine and Health Sciences Morbidity Mortality Patient outcomes Patients Pediatric intensive care Pediatrics Pharmaceutical Preparations - administration & dosage Predictions Protocol (computers) Republic of Korea Research and Analysis Methods Retrospective Studies Side effects Software
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Zusammenfassung:	Despite the high prevalence of potential drug-drug interactions in pediatric intensive care units, their clinical relevance and significance are unclear. We assessed the characteristics and risk factors of clinically relevant potential drug-drug interactions to facilitate their efficient monitoring in pediatric intensive care units. This retrospective cohort study reviewed the medical records of 159 patients aged
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0246754