Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice

Interleukin-34 (IL-34) shares a receptor (cFMS) with colony stimulating factor-1 (CSF-1), and these two ligands mediate macrophage proliferation. However, in contrast to CSF-1, the influence of IL-34 on tubular epithelial cells (TECs) injury remains unclear. We investigated the physiological effects...

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Veröffentlicht in:PloS one 2021-01, Vol.16 (1), p.e0245340
Hauptverfasser: Wada, Yukihiro, Iyoda, Masayuki, Matsumoto, Kei, Suzuki, Taihei, Tachibana, Shohei, Kanazawa, Nobuhiro, Honda, Hirokazu
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Sprache:eng
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