Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study

Limited data are available for clinical characteristics of patients with coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe the clinical characteristics of COVID-19 and identify the risk factors for severe illness of COVID-19 in Jiangsu province, China. Clinical data of...

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Veröffentlicht in:PLoS neglected tropical diseases 2020-05, Vol.14 (5), p.e0008280
Hauptverfasser: Huang, Rui, Zhu, Li, Xue, Leyang, Liu, Longgen, Yan, Xuebing, Wang, Jian, Zhang, Biao, Xu, Tianmin, Ji, Fang, Zhao, Yun, Cheng, Juan, Wang, Yinling, Shao, Huaping, Hong, Shuqin, Cao, Qi, Li, Chunyang, Zhao, Xiang-An, Zou, Lei, Sang, Dawen, Zhao, Haiyan, Guan, Xinying, Chen, Xiaobing, Shan, Chun, Xia, Juan, Chen, Yuxin, Yan, Xiaomin, Wei, Jie, Zhu, Chuanwu, Wu, Chao
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Sprache:eng
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Zusammenfassung:Limited data are available for clinical characteristics of patients with coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe the clinical characteristics of COVID-19 and identify the risk factors for severe illness of COVID-19 in Jiangsu province, China. Clinical data of hospitalized COVID-19 patients were retrospectively collected in 8 hospitals from 8 cities of Jiangsu province, China. Clinical findings of COVID-19 patients were described and risk factors for severe illness of COVID-19 were analyzed. By Feb 10, 2020, 202 hospitalized patients with COVID-19 were enrolled. The median age of patients was 44.0 years (interquartile range, 33.0-54.0). 55 (27.2%) patients had comorbidities. At the onset of illness, the common symptoms were fever (156 [77.2%]) and cough (120 [59.4%]). 66 (32.7%) patients had lymphopenia. 193 (95.5%) patients had abnormal radiological findings. 11 (5.4%) patients were admitted to the intensive care unit and none of the patients died. 23 (11.4%) patients had severe illness. Severe illness of COVID-19 was independently associated with body mass index (BMI) ≥ 28 kg/m2 (odds ratio [OR], 9.219; 95% confidence interval [CI], 2.731 to 31.126; P
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0008280