Madurella mycetomatis causing eumycetoma medical treatment: The challenges and prospects

[...]the most common site of infection is the foot, and the hand ranks second. Treatment of eumycetoma Despite centuries of recognition, the treatment of eumycetoma remains challenging, difficult, and disappointing. [...]there are no definite treatment guidelines or protocols. [...]the treatment is based on personal experiences or a few published case reports and case series [9,10]. Being an azole, itraconazole is contraindicated in pregnancy since it is embryotoxic and teratogenic in animals (Pregnancy Risk Category C) [41]. [...]pregnant women exposed to itraconazole were shown to have an increased risk of early fetal loss [42].