Health related quality of life of people receiving highly active antiretroviral therapy in Southwest Ethiopia

Highly Active Antiretroviral Therapy (HAART) is a standard of HIV management to suppress viral load and delay progression to AIDS. However, questions have been raised about the use of antiretroviral therapy and how it affects quality of life (QoL) of people living with HIV/AIDS (PLWHA). The study he...

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Veröffentlicht in:	PloS one 2020-08, Vol.15 (8), p.e0237013
Hauptverfasser:	Desta, Addisu, Biru, Tessema Tsehay, Kefale, Adane Teshome
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Antiretroviral agents Antiretroviral drugs Antiretroviral Therapy, Highly Active - methods Antiretroviral Therapy, Highly Active - psychology Biology and Life Sciences Care and treatment Cross-Sectional Studies Data collection Developing countries Drug stores Ethiopia - epidemiology Female Health aspects Highly active antiretroviral therapy HIV HIV Infections - drug therapy HIV Infections - psychology HIV patients HIV-1 - metabolism HIV-1 - pathogenicity Human immunodeficiency virus Humans Identification methods LDCs Male Medical records Medicine and Health Sciences Middle Aged Patient compliance Patient outcomes Patients Pharmacy Physical Sciences Quality assessment Quality of life Quality of Life - psychology Questionnaires Regression analysis Research and Analysis Methods Statistical analysis Surveys Surveys and Questionnaires Therapy
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Zusammenfassung:	Highly Active Antiretroviral Therapy (HAART) is a standard of HIV management to suppress viral load and delay progression to AIDS. However, questions have been raised about the use of antiretroviral therapy and how it affects quality of life (QoL) of people living with HIV/AIDS (PLWHA). The study hence aimed to assess the QoL of PLWHA who were taking HAART at Mizan-Tepi University Teaching Hospital (MTUTH) and identify factors associated with QoL. A cross sectional study was conducted among PLWHA receiving HAART at MTUTH from March 04-April 1, 2018. Patients were recruited consecutively and interviewed with structured questionnaire. A data abstraction tool was used to extract data from patient medical records. Quality of life was assessed using the World Health Organization Quality of Life HIV- BREF (WHOQOL-HIV-BREF) standard tool. Data was entered to Epi-Info version 3.5.3 and analyzed using SPSS version 22 for windows. A multivariable logistic regression analysis was fitted to identify factors associated with QoL. A statistical significance was established at a p value
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0237013