A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage

The piRNA pathway protects germline genomes from selfish genetic elements (e.g. transposons) through their transcript cleavage in the cytoplasm and/or their transcriptional silencing in the nucleus. Here, we describe a mechanism by which the nuclear and cytoplasmic arms of the piRNA pathway are link...

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Veröffentlicht in:PLoS genetics 2020-03, Vol.16 (3), p.e1008648-e1008648
Hauptverfasser: Venkei, Zsolt G, Choi, Charlotte P, Feng, Suhua, Chen, Cuie, Jacobsen, Steven E, Kim, John K, Yamashita, Yukiko M
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Sprache:eng
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