Burden of invasive pneumococcal disease among children in rural Mozambique: 2001-2012

Burden of invasive pneumococcal disease among children in rural Mozambique: 2001-2012

Invasive pneumococcal disease (IPD) is a major cause of illness and death among children worldwide. 10-valent pneumococcal conjugate vaccine (PCV10) was introduced as part of the Mozambican routine immunization program in April 2013. We characterized the IPD burden in a rural area of Mozambique befo...

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Veröffentlicht in:PloS one 2018-01, Vol.13 (1), p.e0190687-e0190687
Hauptverfasser: Sigaúque, Betuel, Verani, Jennifer R, Massora, Sérgio, Vubil, Delfino, Quintó, Llorenç, Acácio, Sozinho, Mandomando, Inácio, Bassat, Quique, Nhampossa, Tacilta, Pimenta, Fabiana, Sacoor, Charfudin, Carvalho, Maria da Gloria, Macete, Eusebio, Alonso, Pedro L
Format: Artikel
Sprache:eng
Schlagworte:
Age
Antibiotics
Antimicrobial agents
Biology and Life Sciences
Catchment areas
Causes of
Cerebrospinal fluid
Children
Children & youth
Demographic aspects
Disease control
Disease prevention
Fatalities
HIV
HIV (Viruses)
Hospitals
Human immunodeficiency virus
Immunization
Infants
Medical laboratories
Medical research
Medical tests
Medicine and Health Sciences
Meningitis
Mortality
Mozambique
Moçambic
Pediatric diseases
Pediatrics
People and Places
Pneumonia
Population
Prevention
Respiratory diseases
Risk factors
Rural areas
Serotyping
Streptococcus infections
Surveillance
Vaccines
VIH (Virus)
Viruses
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Zusammenfassung:Invasive pneumococcal disease (IPD) is a major cause of illness and death among children worldwide. 10-valent pneumococcal conjugate vaccine (PCV10) was introduced as part of the Mozambican routine immunization program in April 2013. We characterized the IPD burden in a rural area of Mozambique before PCV introduction and estimated the potential impact of this intervention. We conducted population-based surveillance for IPD, defined as S. pneumoniae isolated from blood or cerebrospinal fluid, among children
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0190687