Prevalence and burden of bronchiectasis in a lung cancer screening program

The prevalence of bronchiectasis in the general population and in individuals undergoing lung cancer screening with low dose computed tomography (LDCT) is unknown. The aim of this study is to estimate the prevalence and impact of bronchiectasis in a screening lung cancer program. 3028 individuals pa...

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Veröffentlicht in:PloS one 2020-04, Vol.15 (4), p.e0231204
Hauptverfasser: Sanchez-Carpintero Abad, Maria, Sanchez-Salcedo, Pablo, de-Torres, Juan P, Alcaide, Ana B, Seijo, Luis M, Pueyo, Jesus, Bastarrika, Gorka, Zulueta, Javier J, Campo, Arantza
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Sprache:eng
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Zusammenfassung:The prevalence of bronchiectasis in the general population and in individuals undergoing lung cancer screening with low dose computed tomography (LDCT) is unknown. The aim of this study is to estimate the prevalence and impact of bronchiectasis in a screening lung cancer program. 3028 individuals participating in an international multicenter lung cancer screening consortium (I-ELCAP) were selected from 2000 to 2012. Patients with bronchiectasis on baseline CT were identified and compared to selected controls. Detection of nodules, need for additional studies and incidence of cancer were analyzed over the follow-up period. The prevalence of bronchiectasis was 11.6%(354/3028). On the baseline LDCT, the number of subjects with nodules identified was 189(53.4%) in patients with bronchiectasis compared to 63(17.8%) in controls (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0231204