Non-resolution of non-alcoholic fatty liver disease (NAFLD) among urban, adult Sri Lankans in the general population: A prospective, cohort follow-up study

There are few studies investigating the natural course of non-alcoholic fatty liver disease (NAFLD) in the community. We assessed resolution of NAFLD in a general population cohort of urban Sri Lankans adults. Participants were selected by age-stratified random sampling from electoral lists. They we...

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Veröffentlicht in:	PloS one 2019-10, Vol.14 (10), p.e0224474-e0224474
Hauptverfasser:	Niriella, Madunil Anuk, Kasturiratna, Anuradhani, Beddage, Thulani, Ediriweera, Dileepa Senajith, De Silva, Shamila Thivanshi, Perera, K Ruwan, Subasinghe, Chamila Erandaka, Kodisinghe, S Kuleesha, Piyaratna, T Chathura, Rishikesawan, Vithiya, Dassanayaka, Anuradha Supun, De Silva, Arjuna Priyadarshin, Pathmeswaran, Arunasalam, Wickramasinghe, Ananda Rajitha, Kato, Norihiro, Janaka de Silva, Hithanadura
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Age Alcohol use Anthropometry Anthropometry - methods Biochemistry Biology and Life Sciences Blood Pressure Body Mass Index Body measurements Cholesterol Cholesterol tests Cohort Studies Criteria Diagnosis Drinking (Alcoholic beverages) Exercise Fatty liver Female Follow-Up Studies Gastroenterology Glycosylated hemoglobin Health aspects Hepatitis Hepatitis B Hepatology High density lipoprotein Hip Humans Hypertension - epidemiology Lifestyles Lipoproteins, HDL Liver Liver - pathology Liver diseases Male Medical research Medicine Medicine and Health Sciences Men Metabolic syndrome Metabolic Syndrome - epidemiology Middle Aged Non-alcoholic Fatty Liver Disease - blood Non-alcoholic Fatty Liver Disease - epidemiology Nutrition research Physical fitness Population Prospective Studies Random sampling Research and Analysis Methods Risk Factors Serological tests Sri Lanka - epidemiology Statistical sampling Studies Teaching hospitals Triglycerides Ultrasonic imaging Ultrasound Ultrasound imaging Urban Population Waist Circumference Waist-Hip Ratio Weight Weight control
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Zusammenfassung:	There are few studies investigating the natural course of non-alcoholic fatty liver disease (NAFLD) in the community. We assessed resolution of NAFLD in a general population cohort of urban Sri Lankans adults. Participants were selected by age-stratified random sampling from electoral lists. They were initially screened in 2007 and re-evaluated in 2014. On both occasions structured interview, anthropometric-measurements, liver ultrasonography, and biochemical/serological tests were performed. NAFLD was diagnosed on ultrasound criteria for fatty liver, safe-alcohol consumption (
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0224474