Emergomyces: The global rise of new dimorphic fungal pathogens

A biopsy of skin tissue demonstrated small budding yeasts, resembling those of Histoplasma capsulatum, in addition to larger pleomorphic cells. [...]the fungus that grew in culture had a dissimilar microscopic appearance [1, 2]. [...]occurring infections of animals have not been demonstrated [22]. Schwartz and colleagues found that intraperitoneal inoculations with Es. africanus were fatal to wild-type mice at doses of 106 conidia, whereas lower doses did not cause disease (although the organism could still be cultured from their livers and spleens with inoculae as low as 102 conidia) [20]. [...]C57BL/6 mice were more susceptible to disease than BALB/c mice [20]. First report of urease activity in the novel systemic fungal pathogen Emergomyces africanus: A comparison with the neurotrope Cryptococcus neoformans.