β-glucan-dependent shuttling of conidia from neutrophils to macrophages occurs during fungal infection establishment

The initial host response to fungal pathogen invasion is critical to infection establishment and outcome. However, the diversity of leukocyte-pathogen interactions is only recently being appreciated. We describe a new form of interleukocyte conidial exchange called "shuttling." In Talaromy...

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Veröffentlicht in:	PLoS biology 2019-09, Vol.17 (9), p.e3000113-e3000113
Hauptverfasser:	Pazhakh, Vahid, Ellett, Felix, Croker, Ben A, O'Donnell, Joanne A, Pase, Luke, Schulze, Keith E, Greulich, R Stefan, Gupta, Aakash, Reyes-Aldasoro, Constantino Carlos, Andrianopoulos, Alex, Lieschke, Graham J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Aspergillosis - immunology Aspergillus fumigatus beta-Glucans - immunology Biology Biology and Life Sciences Cancer Conidia Funding Fungal infections Fungi Fungicides Genetics Genomics Glucan Hematology Host-Pathogen Interactions Infections Leukocytes Leukocytes (neutrophilic) Macrophages Macrophages - physiology Medical research Medicine Medicine and Health Sciences Mice Microorganisms Neurosciences Neutrophils Neutrophils - physiology Niches Pathogens Phagocytes Phagocytosis Phagosomes Research and Analysis Methods Spores, Fungal Supervision Talaromyces Tethering Zebrafish β-Glucan
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