Blood cell markers that can predict the long-term outcomes of patients with colorectal cancer
To identify blood cell markers that predict the long-term outcomes of patients with colorectal cancer. Data from 892 stage II and III colorectal cancer patients who underwent R0 resection were included. We analyzed the correlations of the preoperative blood data, previously reported prognostic indic...
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Veröffentlicht in: | PloS one 2019-08, Vol.14 (8), p.e0220579-e0220579 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | To identify blood cell markers that predict the long-term outcomes of patients with colorectal cancer.
Data from 892 stage II and III colorectal cancer patients who underwent R0 resection were included. We analyzed the correlations of the preoperative blood data, previously reported prognostic indices, and clinicopathologic factors with the long-term outcomes, such as relapse-free survival and overall survival, using univariate and multivariate analyses.
Multivariate analysis showed that tumor location, stage, mean corpuscular volume, neutrophil-to-lymphocyte ratio, and lymphocyte-to- monocyte ratio were significantly correlated with relapse-free survival. A mean corpuscular volume ≥80.5 fL, neutrophil-to-lymphocyte ratio ≥5.5, and lymphocyte-to- monocyte ratio |
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ISSN: | 1932-6203 1932-6203 |
DOI: | 10.1371/journal.pone.0220579 |