Blood cell markers that can predict the long-term outcomes of patients with colorectal cancer

To identify blood cell markers that predict the long-term outcomes of patients with colorectal cancer. Data from 892 stage II and III colorectal cancer patients who underwent R0 resection were included. We analyzed the correlations of the preoperative blood data, previously reported prognostic indic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PloS one 2019-08, Vol.14 (8), p.e0220579-e0220579
Hauptverfasser: Mizuno, Hironori, Yuasa, Norihiro, Takeuchi, Eiji, Miyake, Hideo, Nagai, Hidemasa, Yoshioka, Yuichiro, Miyata, Kanji
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:To identify blood cell markers that predict the long-term outcomes of patients with colorectal cancer. Data from 892 stage II and III colorectal cancer patients who underwent R0 resection were included. We analyzed the correlations of the preoperative blood data, previously reported prognostic indices, and clinicopathologic factors with the long-term outcomes, such as relapse-free survival and overall survival, using univariate and multivariate analyses. Multivariate analysis showed that tumor location, stage, mean corpuscular volume, neutrophil-to-lymphocyte ratio, and lymphocyte-to- monocyte ratio were significantly correlated with relapse-free survival. A mean corpuscular volume ≥80.5 fL, neutrophil-to-lymphocyte ratio ≥5.5, and lymphocyte-to- monocyte ratio
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0220579