Measurement reproducibility of slice-interleaved T1 and T2 mapping sequences over 20 months: A single center study
Quantifying reproducibility of native T1 and T2 mapping over a long period (> 1 year) is necessary to assess whether changes in T1 and T2 over repeated sessions in a longitudinal study are associated with variability due to underlying tissue composition or technical confounders. To carry out a si...
Gespeichert in:
| Veröffentlicht in: | PloS one 2019-07, Vol.14 (7), p.e0220190-e0220190 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0220190 |
|---|---|
| container_issue | 7 |
| container_start_page | e0220190 |
| container_title | PloS one |
| container_volume | 14 |
| creator | Jang, Jihye Ngo, Long H Captur, Gabriella Moon, James C Nezafat, Reza |
| description | Quantifying reproducibility of native T1 and T2 mapping over a long period (> 1 year) is necessary to assess whether changes in T1 and T2 over repeated sessions in a longitudinal study are associated with variability due to underlying tissue composition or technical confounders.
To carry out a single-center phantom study to 1) investigate measurement reproducibility of slice-interleaved T1 (STONE) and T2 mapping over 20 months, 2) quantify sources of variability, and 3) compare reproducibility and measurements against reference spin-echo measurements.
MR imaging was performed on a 1.5 Tesla Philips Achieva scanner every 2-3 weeks over 20 months using the T1MES phantom. In each session, slice-interleaved T1 and T2 mapping was repeated 3 times for 5 slices, and maps were reconstructed using both 2-parameter and 3-parameter fit models. Reproducibility between sessions, and repeatability between repetitions and slices were evaluated using coefficients of variation (CV). Different sources of variability were quantified using variance decomposition analysis. The slice-interleaved measurement was compared to the spin-echo reference and MOLLI.
Slice-interleaved T1 had excellent reproducibility and repeatability with a CV < 2%. The main sources of T1 variability were temperature in 2-parameter maps, and slice in 3-parameter maps. Superior between-session reproducibility to the spin-echo T1 was shown in 2-parameter maps, and similar reproducibility in 3-parameter maps. Superior reproducibility to MOLLI T1 was also shown. Similar measurements to the spin-echo T1 were observed with linear regression slopes of 0.94-0.99, but slight underestimation. Slice-interleaved T2 showed good reproducibility and repeatability with a CV < 7%. The main source of T2 variability was slice location/orientation. Between-session reproducibility was lower than the spin-echo T2 reference and showed good measurement agreement with linear regression slopes of 0.78-1.06.
Slice-interleaved T1 and T2 mapping sequences yield excellent long-term reproducibility over 20 months. |
| doi_str_mv | 10.1371/journal.pone.0220190 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_plos_</sourceid><recordid>TN_cdi_plos_journals_2264436706</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_49411de1eaf444d099927cb466860a99</doaj_id><sourcerecordid>2265766217</sourcerecordid><originalsourceid>FETCH-LOGICAL-c456t-998f30dc3e8b8e881ef4272d39d7ebf43f2165d774937d69738e72e06e381af93</originalsourceid><addsrcrecordid>eNptUstq3DAUNaWlebR_UFpBN9l4qpf16KIQQh-BlG7StZCt64kG2XIle2D-vnbGCUnp6grdc86953KK4h3BG8Ik-bSLU-pt2Ayxhw2mFBONXxSnRDNaCorZyyfvk-Is5x3GFVNCvC5OGGGcY6lOi_QTbJ4SdNCPKMGQopsaX_vgxwOKLcrBN1D6foQUwO7BoVuCbD8Xijo7DL7fogx_JugbyCjuISGKURf78S5_Rpcoz4AAqIFFAeVxcoc3xavWhgxv13pe_P729fbqR3nz6_v11eVN2fBKjKXWqmXYNQxUrUApAi2nkjqmnYS65aylRFROSq6ZdEJLpkBSwAKYIrbV7Lz4cNQdQsxmPVc2lArOmZBYzIjrI8JFuzND8p1NBxOtN_cfMW2NTaNvAhiuOSEOCNiWc-6w1prKpuZCKIGtXqZ9WadNdQduMZxseCb6vNP7O7ONeyNEpUjFZoGLVSDF-Z55NJ3PDYRge4jT_d6VFIISOUM__gP9vzt-RDUp5pygfVyGYLNE6IFllgiZNUIz7f1TI4-kh8ywv2PXxGw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2264436706</pqid></control><display><type>article</type><title>Measurement reproducibility of slice-interleaved T1 and T2 mapping sequences over 20 months: A single center study</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Jang, Jihye ; Ngo, Long H ; Captur, Gabriella ; Moon, James C ; Nezafat, Reza</creator><contributor>Deniz, Cem M.</contributor><creatorcontrib>Jang, Jihye ; Ngo, Long H ; Captur, Gabriella ; Moon, James C ; Nezafat, Reza ; Deniz, Cem M.</creatorcontrib><description>Quantifying reproducibility of native T1 and T2 mapping over a long period (> 1 year) is necessary to assess whether changes in T1 and T2 over repeated sessions in a longitudinal study are associated with variability due to underlying tissue composition or technical confounders.
To carry out a single-center phantom study to 1) investigate measurement reproducibility of slice-interleaved T1 (STONE) and T2 mapping over 20 months, 2) quantify sources of variability, and 3) compare reproducibility and measurements against reference spin-echo measurements.
MR imaging was performed on a 1.5 Tesla Philips Achieva scanner every 2-3 weeks over 20 months using the T1MES phantom. In each session, slice-interleaved T1 and T2 mapping was repeated 3 times for 5 slices, and maps were reconstructed using both 2-parameter and 3-parameter fit models. Reproducibility between sessions, and repeatability between repetitions and slices were evaluated using coefficients of variation (CV). Different sources of variability were quantified using variance decomposition analysis. The slice-interleaved measurement was compared to the spin-echo reference and MOLLI.
Slice-interleaved T1 had excellent reproducibility and repeatability with a CV < 2%. The main sources of T1 variability were temperature in 2-parameter maps, and slice in 3-parameter maps. Superior between-session reproducibility to the spin-echo T1 was shown in 2-parameter maps, and similar reproducibility in 3-parameter maps. Superior reproducibility to MOLLI T1 was also shown. Similar measurements to the spin-echo T1 were observed with linear regression slopes of 0.94-0.99, but slight underestimation. Slice-interleaved T2 showed good reproducibility and repeatability with a CV < 7%. The main source of T2 variability was slice location/orientation. Between-session reproducibility was lower than the spin-echo T2 reference and showed good measurement agreement with linear regression slopes of 0.78-1.06.
Slice-interleaved T1 and T2 mapping sequences yield excellent long-term reproducibility over 20 months.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0220190</identifier><identifier>PMID: 31344078</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Accuracy ; Biology and Life Sciences ; Biomedical research ; Cardiology ; Cardiomyopathy ; Coefficient of variation ; Correlation analysis ; Diagnostic Techniques, Cardiovascular - instrumentation ; Echo surveys ; Electrocardiography - instrumentation ; Electrocardiography - methods ; Heart ; Heart - diagnostic imaging ; Heart Rate - physiology ; Humans ; Image Enhancement - instrumentation ; Image Enhancement - methods ; Image Interpretation, Computer-Assisted - methods ; Longitudinal Studies ; Magnetic resonance imaging ; Magnetic Resonance Imaging - instrumentation ; Magnetic Resonance Imaging - methods ; Mapping ; Measurement methods ; Medical research ; Medicine and Health Sciences ; Methods ; Myocardium - pathology ; NMR ; Nuclear magnetic resonance ; Parameters ; Phantoms, Imaging ; Physical Sciences ; Regression analysis ; Reproducibility ; Reproducibility of Results ; Research and Analysis Methods ; Slopes ; Variability ; Variance analysis</subject><ispartof>PloS one, 2019-07, Vol.14 (7), p.e0220190-e0220190</ispartof><rights>2019 Jang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 Jang et al 2019 Jang et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c456t-998f30dc3e8b8e881ef4272d39d7ebf43f2165d774937d69738e72e06e381af93</citedby><cites>FETCH-LOGICAL-c456t-998f30dc3e8b8e881ef4272d39d7ebf43f2165d774937d69738e72e06e381af93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658153/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658153/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31344078$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Deniz, Cem M.</contributor><creatorcontrib>Jang, Jihye</creatorcontrib><creatorcontrib>Ngo, Long H</creatorcontrib><creatorcontrib>Captur, Gabriella</creatorcontrib><creatorcontrib>Moon, James C</creatorcontrib><creatorcontrib>Nezafat, Reza</creatorcontrib><title>Measurement reproducibility of slice-interleaved T1 and T2 mapping sequences over 20 months: A single center study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Quantifying reproducibility of native T1 and T2 mapping over a long period (> 1 year) is necessary to assess whether changes in T1 and T2 over repeated sessions in a longitudinal study are associated with variability due to underlying tissue composition or technical confounders.
To carry out a single-center phantom study to 1) investigate measurement reproducibility of slice-interleaved T1 (STONE) and T2 mapping over 20 months, 2) quantify sources of variability, and 3) compare reproducibility and measurements against reference spin-echo measurements.
MR imaging was performed on a 1.5 Tesla Philips Achieva scanner every 2-3 weeks over 20 months using the T1MES phantom. In each session, slice-interleaved T1 and T2 mapping was repeated 3 times for 5 slices, and maps were reconstructed using both 2-parameter and 3-parameter fit models. Reproducibility between sessions, and repeatability between repetitions and slices were evaluated using coefficients of variation (CV). Different sources of variability were quantified using variance decomposition analysis. The slice-interleaved measurement was compared to the spin-echo reference and MOLLI.
Slice-interleaved T1 had excellent reproducibility and repeatability with a CV < 2%. The main sources of T1 variability were temperature in 2-parameter maps, and slice in 3-parameter maps. Superior between-session reproducibility to the spin-echo T1 was shown in 2-parameter maps, and similar reproducibility in 3-parameter maps. Superior reproducibility to MOLLI T1 was also shown. Similar measurements to the spin-echo T1 were observed with linear regression slopes of 0.94-0.99, but slight underestimation. Slice-interleaved T2 showed good reproducibility and repeatability with a CV < 7%. The main source of T2 variability was slice location/orientation. Between-session reproducibility was lower than the spin-echo T2 reference and showed good measurement agreement with linear regression slopes of 0.78-1.06.
Slice-interleaved T1 and T2 mapping sequences yield excellent long-term reproducibility over 20 months.</description><subject>Accuracy</subject><subject>Biology and Life Sciences</subject><subject>Biomedical research</subject><subject>Cardiology</subject><subject>Cardiomyopathy</subject><subject>Coefficient of variation</subject><subject>Correlation analysis</subject><subject>Diagnostic Techniques, Cardiovascular - instrumentation</subject><subject>Echo surveys</subject><subject>Electrocardiography - instrumentation</subject><subject>Electrocardiography - methods</subject><subject>Heart</subject><subject>Heart - diagnostic imaging</subject><subject>Heart Rate - physiology</subject><subject>Humans</subject><subject>Image Enhancement - instrumentation</subject><subject>Image Enhancement - methods</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Longitudinal Studies</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - instrumentation</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Mapping</subject><subject>Measurement methods</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Methods</subject><subject>Myocardium - pathology</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Parameters</subject><subject>Phantoms, Imaging</subject><subject>Physical Sciences</subject><subject>Regression analysis</subject><subject>Reproducibility</subject><subject>Reproducibility of Results</subject><subject>Research and Analysis Methods</subject><subject>Slopes</subject><subject>Variability</subject><subject>Variance analysis</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNptUstq3DAUNaWlebR_UFpBN9l4qpf16KIQQh-BlG7StZCt64kG2XIle2D-vnbGCUnp6grdc86953KK4h3BG8Ik-bSLU-pt2Ayxhw2mFBONXxSnRDNaCorZyyfvk-Is5x3GFVNCvC5OGGGcY6lOi_QTbJ4SdNCPKMGQopsaX_vgxwOKLcrBN1D6foQUwO7BoVuCbD8Xijo7DL7fogx_JugbyCjuISGKURf78S5_Rpcoz4AAqIFFAeVxcoc3xavWhgxv13pe_P729fbqR3nz6_v11eVN2fBKjKXWqmXYNQxUrUApAi2nkjqmnYS65aylRFROSq6ZdEJLpkBSwAKYIrbV7Lz4cNQdQsxmPVc2lArOmZBYzIjrI8JFuzND8p1NBxOtN_cfMW2NTaNvAhiuOSEOCNiWc-6w1prKpuZCKIGtXqZ9WadNdQduMZxseCb6vNP7O7ONeyNEpUjFZoGLVSDF-Z55NJ3PDYRge4jT_d6VFIISOUM__gP9vzt-RDUp5pygfVyGYLNE6IFllgiZNUIz7f1TI4-kh8ywv2PXxGw</recordid><startdate>20190725</startdate><enddate>20190725</enddate><creator>Jang, Jihye</creator><creator>Ngo, Long H</creator><creator>Captur, Gabriella</creator><creator>Moon, James C</creator><creator>Nezafat, Reza</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20190725</creationdate><title>Measurement reproducibility of slice-interleaved T1 and T2 mapping sequences over 20 months: A single center study</title><author>Jang, Jihye ; Ngo, Long H ; Captur, Gabriella ; Moon, James C ; Nezafat, Reza</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c456t-998f30dc3e8b8e881ef4272d39d7ebf43f2165d774937d69738e72e06e381af93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Accuracy</topic><topic>Biology and Life Sciences</topic><topic>Biomedical research</topic><topic>Cardiology</topic><topic>Cardiomyopathy</topic><topic>Coefficient of variation</topic><topic>Correlation analysis</topic><topic>Diagnostic Techniques, Cardiovascular - instrumentation</topic><topic>Echo surveys</topic><topic>Electrocardiography - instrumentation</topic><topic>Electrocardiography - methods</topic><topic>Heart</topic><topic>Heart - diagnostic imaging</topic><topic>Heart Rate - physiology</topic><topic>Humans</topic><topic>Image Enhancement - instrumentation</topic><topic>Image Enhancement - methods</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>Longitudinal Studies</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - instrumentation</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Mapping</topic><topic>Measurement methods</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Methods</topic><topic>Myocardium - pathology</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Parameters</topic><topic>Phantoms, Imaging</topic><topic>Physical Sciences</topic><topic>Regression analysis</topic><topic>Reproducibility</topic><topic>Reproducibility of Results</topic><topic>Research and Analysis Methods</topic><topic>Slopes</topic><topic>Variability</topic><topic>Variance analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jang, Jihye</creatorcontrib><creatorcontrib>Ngo, Long H</creatorcontrib><creatorcontrib>Captur, Gabriella</creatorcontrib><creatorcontrib>Moon, James C</creatorcontrib><creatorcontrib>Nezafat, Reza</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jang, Jihye</au><au>Ngo, Long H</au><au>Captur, Gabriella</au><au>Moon, James C</au><au>Nezafat, Reza</au><au>Deniz, Cem M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Measurement reproducibility of slice-interleaved T1 and T2 mapping sequences over 20 months: A single center study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2019-07-25</date><risdate>2019</risdate><volume>14</volume><issue>7</issue><spage>e0220190</spage><epage>e0220190</epage><pages>e0220190-e0220190</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Quantifying reproducibility of native T1 and T2 mapping over a long period (> 1 year) is necessary to assess whether changes in T1 and T2 over repeated sessions in a longitudinal study are associated with variability due to underlying tissue composition or technical confounders.
To carry out a single-center phantom study to 1) investigate measurement reproducibility of slice-interleaved T1 (STONE) and T2 mapping over 20 months, 2) quantify sources of variability, and 3) compare reproducibility and measurements against reference spin-echo measurements.
MR imaging was performed on a 1.5 Tesla Philips Achieva scanner every 2-3 weeks over 20 months using the T1MES phantom. In each session, slice-interleaved T1 and T2 mapping was repeated 3 times for 5 slices, and maps were reconstructed using both 2-parameter and 3-parameter fit models. Reproducibility between sessions, and repeatability between repetitions and slices were evaluated using coefficients of variation (CV). Different sources of variability were quantified using variance decomposition analysis. The slice-interleaved measurement was compared to the spin-echo reference and MOLLI.
Slice-interleaved T1 had excellent reproducibility and repeatability with a CV < 2%. The main sources of T1 variability were temperature in 2-parameter maps, and slice in 3-parameter maps. Superior between-session reproducibility to the spin-echo T1 was shown in 2-parameter maps, and similar reproducibility in 3-parameter maps. Superior reproducibility to MOLLI T1 was also shown. Similar measurements to the spin-echo T1 were observed with linear regression slopes of 0.94-0.99, but slight underestimation. Slice-interleaved T2 showed good reproducibility and repeatability with a CV < 7%. The main source of T2 variability was slice location/orientation. Between-session reproducibility was lower than the spin-echo T2 reference and showed good measurement agreement with linear regression slopes of 0.78-1.06.
Slice-interleaved T1 and T2 mapping sequences yield excellent long-term reproducibility over 20 months.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>31344078</pmid><doi>10.1371/journal.pone.0220190</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2019-07, Vol.14 (7), p.e0220190-e0220190 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2264436706 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Accuracy Biology and Life Sciences Biomedical research Cardiology Cardiomyopathy Coefficient of variation Correlation analysis Diagnostic Techniques, Cardiovascular - instrumentation Echo surveys Electrocardiography - instrumentation Electrocardiography - methods Heart Heart - diagnostic imaging Heart Rate - physiology Humans Image Enhancement - instrumentation Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Longitudinal Studies Magnetic resonance imaging Magnetic Resonance Imaging - instrumentation Magnetic Resonance Imaging - methods Mapping Measurement methods Medical research Medicine and Health Sciences Methods Myocardium - pathology NMR Nuclear magnetic resonance Parameters Phantoms, Imaging Physical Sciences Regression analysis Reproducibility Reproducibility of Results Research and Analysis Methods Slopes Variability Variance analysis |
| title | Measurement reproducibility of slice-interleaved T1 and T2 mapping sequences over 20 months: A single center study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T17%3A12%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Measurement%20reproducibility%20of%20slice-interleaved%20T1%20and%20T2%20mapping%20sequences%20over%2020%20months:%20A%20single%20center%20study&rft.jtitle=PloS%20one&rft.au=Jang,%20Jihye&rft.date=2019-07-25&rft.volume=14&rft.issue=7&rft.spage=e0220190&rft.epage=e0220190&rft.pages=e0220190-e0220190&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0220190&rft_dat=%3Cproquest_plos_%3E2265766217%3C/proquest_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2264436706&rft_id=info:pmid/31344078&rft_doaj_id=oai_doaj_org_article_49411de1eaf444d099927cb466860a99&rfr_iscdi=true |