Fast and robust deconvolution of tumor infiltrating lymphocyte from expression profiles using least trimmed squares

Gene-expression deconvolution is used to quantify different types of cells in a mixed population. It provides a highly promising solution to rapidly characterize the tumor-infiltrating immune landscape and identify cold cancers. However, a major challenge is that gene-expression data are frequently...

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Veröffentlicht in:PLoS computational biology 2019-05, Vol.15 (5), p.e1006976-e1006976
Hauptverfasser: Hao, Yuning, Yan, Ming, Heath, Blake R, Lei, Yu L, Xie, Yuying
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Sprache:eng
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