Continued poxvirus research: From foe to friend

The eradication of smallpox is one of the greatest medical successes in history. Vaccinia virus was made famous by being the virus used in the live vaccine that enabled this feat. Nearly 40 years on from that success, this prototypical poxvirus continues to empower the exploration of fundamental bio...

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Veröffentlicht in:	PLoS biology 2019-01, Vol.17 (1), p.e3000124-e3000124
1. Verfasser:	Bidgood, Susanna R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biology Biology and life sciences Breast cancer Cell cycle Cell growth Control Deoxyribonucleic acid DNA DNA viruses Ebola virus Humans Immunization Kinases Medicine and Health Sciences Microbiological research Microscopy Poxviridae - pathogenicity Poxviridae Infections - metabolism Proteins Research - trends Research Matters Smallpox Smallpox - virology Vaccination - methods Vaccination - trends Vaccines Vaccines, Attenuated Vaccinia virus - metabolism Vaccinia virus - pathogenicity Viruses
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Beschreibung
Zusammenfassung:	The eradication of smallpox is one of the greatest medical successes in history. Vaccinia virus was made famous by being the virus used in the live vaccine that enabled this feat. Nearly 40 years on from that success, this prototypical poxvirus continues to empower the exploration of fundamental biology and the potential to develop therapeutics against some of the major causes of death and disease in the modern world.
ISSN:	1545-7885 1544-9173 1545-7885
DOI:	10.1371/journal.pbio.3000124