Liver-related events and mortality among elderly patients with advanced chronic hepatitis C treated with direct-acting antivirals

Direct-acting antivirals (DAAs) are effective in patients aged ≥65 years. However, little is known about the effects of DAAs on survival, liver decompensation and development of hepatocellular carcinoma (HCC). To compare the incidence of liver-related events and mortality between patients aged ≥65 a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2019-06, Vol.14 (6), p.e0217052-e0217052
Hauptverfasser:	Rodríguez-Osorio, Iria, Mena, Alvaro, Meijide, Héctor, Morano, Luis, Delgado, Manuel, Cid, Purificación, Margusino, Luis, Pedreira, José Domingo, Castro, Ángeles
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antiviral agents Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Antiviral drugs Biology and Life Sciences Cancer Carcinogenesis Carcinoma Carcinoma, Hepatocellular - complications Carcinoma, Hepatocellular - pathology Cirrhosis Complications and side effects Cost analysis Development and progression Drug therapy Elderly patients Epidemiology Female Geriatrics Health aspects Hepatitis Hepatitis C Hepatitis C, Chronic - complications Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - mortality Hepatocellular carcinoma Hepatology Humans Incidence Infections Interferon Liver Liver - drug effects Liver - pathology Liver cancer Liver cirrhosis Liver Neoplasms - complications Liver Neoplasms - pathology Liver transplants Male Medical research Medicine and Health Sciences Middle Aged Mortality Older people Patient outcomes Patients People and Places Studies Transplants & implants
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Direct-acting antivirals (DAAs) are effective in patients aged ≥65 years. However, little is known about the effects of DAAs on survival, liver decompensation and development of hepatocellular carcinoma (HCC). To compare the incidence of liver-related events and mortality between patients aged ≥65 and
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0217052